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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2098154Generated: October 25, 2026

4-Methoxyphenylacetic Acid → N-(3-cyanothiophen-2-yl)-2-(4-methoxyphenyl)acetamide

https://huagongshe.com/reaction/2098154

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant2-Aminothiophene-3-carbonitrileHCID 736607—
ProductN-(3-cyanothiophen-2-yl)-2-(4-methoxyphenyl)acetamideHCID 2404093—

Reaction Steps

N-(3-cyanothiophen-2-yl)-2-(4-methoxyphenyl)acetamide was prepared from 2-(4-methoxyphenyl)acetic acid (1.37 g, 8.29 mmol) and 2-aminothiophene-3-carbonitrile (1.03 g, 8.29 mmol) according to protocol B. Retention time (min)=2.150, method [1], MS (ESI) 273.0 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08450363B2
Source datasetuspto-grants-2013_05
ORD IDord-f0dd1448af164d6a98d36693b06f478f
Source noteuspto-grants-2013_05