Acetone → {4-[3-(1-Cyclohexylmethyl-5,6-difluoro-1H-benzoimidazol-2-yl)-pyridin-2-yloxymethyl]-phenoxy}-acetic acid methyl ester
Reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[CH3:32][O:33][C:34]([CH2:35][O:36][c:37]1[cH:38][cH:39][c:40]([CH2:43][Br:44])[cH:41][cH:42]1)=[O:45].[CH3:46][C:47](=[O:48])[CH3:49].[CH:1]1([CH2:7][n:8]2[c:9](-[c:19]3[c:20]([OH:25])[n:21][cH:22][cH:23][cH:24]3)[n:10][c:11]3[c:12]2[cH:13][c:14]([F:18])[c:15]([F:17])[cH:16]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[Cs+:30].[Cs+:31]>>[CH:1]1([CH2:7][n:8]2[c:9](-[c:19]3[c:20]([O:25][CH2:43][c:40]4[cH:39][cH:38][c:37]([O:36][CH2:35][C:34]([O:33][CH3:32])=[O:45])[cH:42][cH:41]4)[n:21][cH:22][cH:23][cH:24]3)[n:10][c:11]3[c:12]2[cH:13][c:14]([F:18])[c:15]([F:17])[cH:16]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cceb75ab3af64da7b282871daed1aeaa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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