HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3-nitrothiophene → 2-Methyl-4-(3-nitrothiophen-2-yl)-1-trityl-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3-nitrothiophene | HCID 220186 | — |
| Reactant | 2-methyl-4-(Tributylstannyl)-1-trityl-1H-imidazole | HCID 68785138 | — |
| Product | 2-Methyl-4-(3-nitrothiophen-2-yl)-1-trityl-1H-imidazole | HCID 68786947 | — |
Reaction Steps
The title compound was prepared from 2-methyl-4-(tributylstannyl)-1-trityl-1H-imidazole and 2-chloro-3-nitrothiophene using protocol E (3.43 g, 76% over 2 steps). Method [7] Retention time 8.87 min by HPLC (M+Na=474).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450363B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-8145d602cc7f478e8ed1f9d41d804895 |
| Source note | uspto-grants-2013_05 |