HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylacetylene → Tert-butyl 3-(3-(cyclopentylethynyl)phenyl)-3-hydroxypropylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylacetylene | HCID 136725 | — |
| Reactant | Tert-butyl 3-(3-bromophenyl)-3-hydroxypropylcarbamate | HCID 57608439 | — |
| Product | Tert-butyl 3-(3-(cyclopentylethynyl)phenyl)-3-hydroxypropylcarbamate | HCID 57608534 | — |
Reaction Steps
Coupling of ethynylcyclopentane (40) with tert-butyl 3-(3-bromophenyl)-3-hydroxypropylcarbamate (39) following the method used in the synthesis of Example 13 gave tert-butyl 3-(3-(cyclopentylethynyl)phenyl)-3-hydroxypropylcarbamate (41) as a brown oil. Yield (0.386 g, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450527B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-08f2721c961848309d91af9a0b87f65e |
| Source note | uspto-grants-2013_05 |