huagongshe.com
HRID2098713

反应详情

EQUATION

反应方程式

HRID 2098713 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cccc3[nH]ncc23)OC1(C)C
HCID45480186

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

C13H17BN2O2

结构：CC(C)(C)OC(=O)Nc1cc2nc(Cl)nc(N3CCOCC3)c2s1
HCID59592872

未命名化合物

PRODUCTS

生成物

1
结构：Nc1cc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2s1
HCID59592924

未命名化合物

PROCEDURE

实验过程

Tert-butyl 2-chloro-4-morpholinothieno[3,2-d]pyrimidin-6-ylcarbamate (50 mg) was coupled to 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole 7 via General Procedure A. The product was purified by reverse phase HPLC to yield 8.8 mg of 225. MS (Q1) 353 (M)+

WORKUP

后处理

  1. customThe product was purified by reverse phase HPLC