HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → 2-(1H-indazol-4-yl)-N-isobutyl-4-morpholinothieno[3,2-d]pyrimidine-6-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | 2-(1H-Indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidine-6-carboxylic acid | HCID 59593141 | — |
| Product | 2-(1H-indazol-4-yl)-N-isobutyl-4-morpholinothieno[3,2-d]pyrimidine-6-carboxamide | HCID 59593049 | — |
Reaction Steps
2-(1H-Indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidine-6-carboxylic acid 13 (30 mg) was coupled to 2-methylpropan-1-amine via General Procedure B. The product was purified via reverse phase HPLC to give 13.2 mg of 256. MS (Q1) 436.8 (M)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450315B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-6810075b416e4dd2b434fd551373ee3a |
| Source note | uspto-grants-2013_05 |