HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridine → HCID 59592988, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo(2,3-b)pyridine | HCID 24208789 | — |
| Reactant | {3-[(2-Hydroxyethyl)sulfamoyl]phenyl}boronic acid | HCID 44119345 | — |
| Reactant | 2-Chloro-6-iodo-7-methyl-4-morpholinothieno[3,2-d]pyrimidine | HCID 59592880 | — |
| Product | HCID 59592988 | HCID 59592988 | — |
Reaction Steps
2-Chloro-6-iodo-7-methyl-4-morpholinothieno[3,2-d]pyrimidine (50 mg) was coupled to N-(2-hydroxyethyl)-3-boronobenzene sulfonamide, and then reacted with 7-azaindole-5-boronic acid pinacol ester via General Procedure F. The product was purified by reverse phase HPLC to yield 17.7 mg of 423. MS (Q1) 551.1 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450315B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-61e77e4bed9f42c590c64da78fba3936 |
| Source note | uspto-grants-2013_05 |