HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 53256703, compound → HCID 57467627, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 53256703 | HCID 53256703 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 57467627 | HCID 57467627 | — |
Reaction Steps
To a flask with methyl 3-(cyclopropyl(hydroxy)methyl)-4-hydroxybenzoate (T20.2) (845 mg, 0.38 mmol) was added manganese (IV) oxide (1.65 g, 1.9 mmol). Then dioxane 3.5 mL was added and the reaction was heated at reflux for 4 hours. The reaction was filtered and concentrated and silica gel chromatography afforded 693 mg of T20.3 (83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08450522B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-e3f8ec9ae4694b2ba638fd09d4921dfe |
| Source note | uspto-grants-2013_05 |