HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethinylestradiol → Ethinyl Estradiol beta-cyclodextrin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethinylestradiol | HCID 5991 | — |
| Reactant | beta-Cyclodextrin | HCID 444041 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Water | HCID 962 | — |
| Product | Ethinyl Estradiol beta-cyclodextrin | HCID 10214247 | — |
Reaction Steps
Process 2 (P2): Ethinyl estradiol is dissolved in acetone. β-cyclodextrin is dissolved at 45 C in water. The ethinyl estradiol solution is added to the beta-cyclodextrin solution. The obtained suspension is stirred for some hours at temperatures below 25 ° C. Afterwards, the crystallization product is isolated and dried by methods described infra.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07569557B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-44d925ad37c141fdba94f1ab2d366faf |
| Source note | uspto-grants-2009_08 |