HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57489618, compound → Benzyl 4-(4-aminophenyl)piperazine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57489618 | HCID 57489618 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Benzyl 4-(4-aminophenyl)piperazine-1-carboxylate | HCID 57489619 | — |
Reaction Steps
11.28 g (33.04 mmol) benzyl 4-(4-nitro-phenyl)-piperazine-1-carboxylate are dissolved in 500 mL methanol and combined with 1 g Raney nickel. The mixture is hydrogenated for 18 h at 5 bar hydrogen pressure. Then the catalyst is filtered off and the residue is combined with 70 mL of aqueous 1 N hydrochloric acid and the solvent is eliminated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07569561B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-bee9cda571c04bf683c6eeccc6dcf620 |
| Source note | uspto-grants-2009_08 |