Aniline → HCID 11552725, compound

Participants

Reaction Conditions

Reaction Steps

The mixture of 3-(6-chloro-purin-9-yl)-N-cyclopropyl-4-methyl-benzamide (10 mg, 0.029 mmol) and aniline (14 mg, 0.15 mmol) in 0.2 mL of dioxane was heated with microwave at 140° C. for 20 minutes. It was then cooled to RT and purified by HPLC give the title compound as an off-white solid (5.2 mg, 46%). HPLC tR=2.09 min; MS m/z 385 [M+H]+.

Provenance & Evidence