Dimethylformamide → HCID 68532721, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3-(6-Chloro-purin-9-yl)-N-cyclopropyl-4-methyl-benzamide (Example 4B) (21 mg, 0.064 mmol) in DMF (0.2 ml) was added cyclopentanol (59 □1, 0.64 mmol). The mixture was heated with microwave at 150° C. for 30 minutes. It was cooled to RT and then purified by PTLC or HPLC to give the desired as a white solid (10 mg, 0.027 mmol, 41%). HPLC tR=2.09 min; MS m/z 386 [M+H]+.

Provenance & Evidence