HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-(2-(Ethylamino)propyl)-1,2-benzenediol hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | [2-(3,4-Dimethoxy-phenyl)-1-methyl-ethyl]-ethyl amine | HCID 22061570 | — |
| Product | 4-(2-(Ethylamino)propyl)-1,2-benzenediol hydrobromide | HCID 130356 | — |
Reaction Steps
A solution of 1.1 g (4.92 mmol) of 2A in 10 mL of 48% HBr was heated to reflux under argon atmosphere for 3.5 hours and then concentrated to dryness under reduced pressure. To this was added 50 mL of dichloromethane and concentrated to dryness under reduced pressure to give crude 2B as a dark brown powder (M+Na, 318).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07569676B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-1b9609bfe6814631b914b313d1b6d23a |
| Source note | uspto-grants-2009_08 |