Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Terephthalaldehyde | HCID 12173 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 4-Thiazolidinone, 3-methyl-2-thioxo- | HCID 72900 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 1200985 | HCID 1200985 | 72.6% |
Reaction Steps
A catalytic amount of ammonium chloride was added into 100 ml acetic acid solution containing terephthaldicarboxaldehyde (1.34 g) and 3-methylrhodanine (1.53 g), followed by about 12 hours of heating at 110° C. After cooling upon standing, the formed yellow crystals were collected by filtration, washed with an appropriate amount of ethanol-water (10:1), and dried to obtain 4-(3-methyl-4-oxo-2-thioxothiazolidin-5-ylidenmethyl)benzaldehyde (1.91 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07569688B2 |
|---|
| Source dataset | uspto-grants-2009_08 |
|---|
| ORD ID | ord-00cedc17198b48f7949be770c28e1368 |
|---|
| Source note | uspto-grants-2009_08 |
|---|
