HRID2099865

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID60966

Tetramethylammonium hydroxide

C4H13NO

结构：C=CC[N+]1([C@H]2C[C@H]3[C@@H]4CC[C@H]5C[C@H](O)[C@@H](N6CCOCC6)C[C@]5(C)[C@H]4CC[C@]3(C)[C@H]2OC(C)=O)CCCC1.[Br-]

HCID441351

Rocuronium bromide

C32H53BrN2O4

PRODUCTS

生成物

结构：C[C@]12C[C@H]3O[C@H]3C[C@@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)[C@@H](N3CCCC3)C[C@@H]12

HCID16063872

(2alpha,3alpha,5alpha,16beta,17beta)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol

C23H37NO2

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

Analysis of rocuronium bromide, Compound I, was performed with a column & packing Hypersil silica; 5 μm, 250 mm×4.6 mm, Cat No. 30005-254630 or equivalent. Eluent A was tetramethylammonium hydroxide Buffer, 0.05M, pH 7.4, eluent B was acetonitrile, and the composition was 10:90, A:B. The stop time was 25 min., the flow rate was 2.0 mL/min., the detector was UV at 210 mn, the column temperature was 30° C., and the injection volume was 5 μl.

WORKUP

后处理

customwas 30° C.