1,1'-(Chlorophenylmethylene)bis(4-methoxybenzene) → HCID 131727558, compound

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Reaction Steps

To a solution of compound 55 (1 mmol) in anhydrous pyridine (4 mL) was added 4,4′-dimethoxytrityl chloride (1.5 mmol). After stirring at room temperature for 6 hours the mixture was quenched with MeOH and then concentrated in vacuo. The residue was dissolved in CH2Cl2 (100 mL), washed with saturated aqueous NaHCO3 (2×20 mL), brine (20 mL) and the organic layer dried over Na2SO4, filtered, and evaporated. The residue was purified by silica gel chromatography. Appropriate fractions were collected, concentrated to give compound 56 in 80% yield.

Provenance & Evidence