Tetrabutylammonium Fluoride → HCID 68903408, compound

Participants

Reaction Steps

Compound 110 (8.7 g) was dissolved in anhydrous THF (80 mL) and TBAF (5.05 g, 20 mL of 1 M solution in THF) was added and the reaction mixture stirred at room temperature for 3 hours at which time the reaction was complete. The solvent was carefully removed and the residue purified on silica gel column to give Compound 111 in 90% yield.

Provenance & Evidence