HCID 178472761, compound → HCID 178472761, compound

HRID 2099916Notes

Reaction equation

HRID 2099916 reaction equation
[OH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:8][CH:9]=2)[C:4](=[O:17])[C:3]=1[C:18]([NH:20][CH2:21][C:22]([O:24]CC)=[O:23])=[O:19].[Br:27][C:28]1[CH:36]=[C:35]2[C:31]([C:32]([OH:47])=[C:33]([C:38]([NH:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43])=[O:39])[C:34]2=[O:37])=[CH:30][CH:29]=1>>[OH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)=[CH:8][CH:9]=2)[C:4](=[O:17])[C:3]=1[C:18]([NH:20][CH2:21][C:22]([OH:24])=[O:23])=[O:19].[Br:27][C:28]1[CH:36]=[C:35]2[C:31]([C:32]([OH:47])=[C:33]([C:38]([NH:40][CH2:41][C:42]([O:44][CH2:45][CH3:46])=[O:43])=[O:39])[C:34]2=[O:37])=[CH:30][CH:29]=1

Participants

4

Reactant 2

HCID 178472761HCID 178472761, compoundHCID 178472762HCID 178472762, compound

Product 2

HCID 178472761HCID 178472761, compoundHCID 178525887HCID 178525887, compound

Procedure

ethyl 2-(3-hydroxy-1-oxo-6-phenyl-1H-indene-2-carboxamido)acetate. The title compound was prepared by a method analogous to Method 2(a) using ethyl 2-(6-bromo-3-hydroxy-1-oxo-1H-indene-2-carboxamido)acetate as starting material. Ethyl 2-(6-bromo-3-hydroxy-1-oxo-1H-indene-2-carboxamido)acetate was prepared by Method 1, as in Example 2.

Sources & evidence

ORD record
ord-62836ba1b8794abfbfb527f1e078d2cb
Source dataset
uspto-grants-2009_08
Patent number
US07569726B2

Reaction notes

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