HCID 57794212, compound → HCID 57794356, compound

Participants

Reaction Steps

Ethyl isothianate (36 mg) was added dropwise to a solution of the compound of Example 97 (0.10 g) in pyridine (1.00 ml) and the mixture was stirred at room temperature for 18 hours. After distilling off the solvent under reduced pressure, the obtained residue was partitioned between ethyl acetate and water, and the organic layer was washed with saturated brine and then dried over anhydride magnesium sulfate. The residue obtained by distilling off the solvent under the reduced pressure was recrystallized from methanol to give the title compound (0.06 g, 56%).

Provenance & Evidence