HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthoyl chloride → 3-{4-[(Naphthalene-2-carbonyl)-amino]-phenyl)-acrylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthoyl chloride | HCID 75246 | — |
| Reactant | 2-Propenoic acid, 3-(4-aminophenyl)-, methyl ester | HCID 3017578 | — |
| Product | 3-{4-[(Naphthalene-2-carbonyl)-amino]-phenyl)-acrylic acid methyl ester | HCID 66958345 | — |
Reaction Steps
Using an analogous method (H4), the title compound was prepared from 2-naphthalenecarbonyl chloride (0.557 g, 2.91 mmol) and 3-(4-amino-phenyl)-acrylic acid methyl ester (3) in a form of white solid (0.950 g, 75%). 1H NMR (DMSO-d6, HMDSO), δ: 3.65 (3H, s); 6.51 (1H, d, J=16.0 Hz); 7.47-8.25 (12H, m); 10.63 (1H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07569724B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-7e82ce5b8615444ba2b166c5f7d184c2 |
| Source note | uspto-grants-2009_08 |