Potassium Carbonate → 3-(Pyrrolidin-1-yl)benzene-1,2-dicarbonitrile

Participants

Reaction Steps

A mixture of 3-nitrophthalonitrile (985 mg, 5.69 mmol), freshly dried potassium carbonate (3.0 g, 21 mmol) and pyrrolidine (15 mL) were heated at reflux for 4 h. The reaction mixture was poured into water (250 mL) to precipitate the product, and this was filtered off, washed with water, and dried to give 1 as an olive-brown powder (633 mg, 56%).

Provenance & Evidence