Lauryldimethylamine → HCID 86760930, compound

Participants

Reaction Steps

2-Chloroethylisocyanate (0.2 ml; 2 mmol) was added to a solution of BHAlyslys2lys4lys8lys16.32CF3COOH (300 mg) in dry DMSO (5 ml) and then N,N-Dimethyl-N-dodecylamine (3.0 ml) was added and the solution stirred overnight at room temperature under nitrogen. The resulting inhomogeneous mixture was then heated at 80° C. for 3 days. The mixture was then cooled and concentrated under high vacuum to give viscous oil. The crude product was purified by gel filtration (Sephadex LH20; 2.5×50 cm; MeOH) to give the product as a viscous oil.

Provenance & Evidence