Thiophosgene → HCID 85844959, compound

HRID 2100232Notes

Reaction equation

HRID 2100232 reaction equation
Cl.[NH2:2][C:3]1[CH:8]=[C:7]([P:9]([OH:12])(=[O:11])[OH:10])[CH:6]=[C:5]([P:13]([OH:16])(=[O:15])[OH:14])[CH:4]=1.[C:17](Cl)(Cl)=[S:18]>O>[N:2]([C:3]1[CH:8]=[C:7]([P:9]([OH:10])(=[O:12])[OH:11])[CH:6]=[C:5]([P:13]([OH:16])(=[O:14])[OH:15])[CH:4]=1)=[C:17]=[S:18]

Participants

4

Reactant 2

HCID 10040ThiophosgeneHCID 85844955HCID 85844955, compound

Product 1

HCID 85844959HCID 85844959, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
20 °C

Procedure

Aniline-3,5-diphosphonic acid hydrochloride(500 mg, 1.73 mmole) was dissolved in water(5 ml) and thiophosgene(600 mg, 5.2 mmole) was added and the mixture stirred vigorously at 20° C. for 2.5 hours. Volatiles were removed in vacuo and the residue was dissolved in water(10 ml), filtered and lyophilised. 490 mg. 96%

Workup

  1. customVolatiles were removed in vacuo
  2. dissolutionthe residue was dissolved in water(10 ml)
  3. filtrationfiltered

Sources & evidence

ORD record
ord-77256170543f47ff8d01a7322d66476b
Source dataset
uspto-grants-2009_08
Patent number
US07572459B2

Reaction notes

Loading…