HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 10201592, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Chloro-3-methyl-6-(pyrimidin-4-YL)pyrimidin-4-one | HCID 17954460 | — |
| Reactant | (4-Chlorobenzoyl)piperidine hydrochloride | HCID 17954461 | — |
| Product | HCID 10201592 | HCID 10201592 | 92% |
Reaction Steps
A solution of (4-Chlorobenzoyl)piperidine hydrochloride (140 mg, 0.539 mmol), 2-chloro-3-methyl-6-(4-pyrimidyl)-pyrimidine-4-one (120 mg, 0.539 mmol) and triethylamine (0.188 ml, 1.35 mmol) in N,N-dimethylformamide(2 ml) was stirred at room temperature. After stirring for several hours, water was added to the reaction mixture. The precipitate was filtered, washed with water and dried to give the title compound (204 mg, 92%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572793B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-090bb8de16bd4757a2ac772d0678b732 |
| Source note | uspto-grants-2009_08 |