Ammonium Chloride → HCID 57798963, compound

Participants

Reaction Steps

To a solution of (bis(benzyloxy)phosphoryloxy)methyl-cyclopropyl(4-methyl-3-nitrobenzoyl)carbamate (0.53 g, 1.0 mmol) in MeOH/THF (1:1, 50 mL) under nitrogen were added ammonium chloride (0.79 g, 14.8 mmol) and zinc (0.75 g, 11.5 mmol). After 3 h, the precipitate was filtered, and the filtrate was concentrated in vacuo, diluted with EtOAc and washed with water (2×), brine successively, dried over Na2SO4, filtered, and concentrated in vacuo to give the title compound as a colorless oil (0.51 g, 100% yield). (M+H)+=525.19.

Provenance & Evidence