Thionyl Chloride → 4-Bromo-3-nitrobenzoyl chloride

HRID 2100383Notes

Reaction equation

HRID 2100383 reaction equation
[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].S(Cl)([Cl:16])=O>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:16])=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 2329864-Bromo-3-nitrobenzoic acid

Product 1

HCID 214065444-Bromo-3-nitrobenzoyl chloride

Procedure

4-Bromo-3-nitrobenzoic acid (500 mg) in thionyl chloride (3 ml) was heated at 110° C. for 2 hrs. The excess thionyl chloride was evaporated in vacuo to give 4-bromo-3-nitrobenzoyl chloride as a yellow solid (502 mg).

Workup

  1. customThe excess thionyl chloride was evaporated in vacuo

Sources & evidence

ORD record
ord-b25725bda97c47678e626f946a4bf3fb
Source dataset
uspto-grants-2009_08
Patent number
US07572790B2

Reaction notes

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