5-(4-Fluoro-phenyl)-4-methyl-pent-4-enoic acid ethyl ester → 5-(4-Fluoro-phenyl)-4-methyl-pentanoic acid ethyl ester

関与物質

反応手順

A slurry of palladium on charcoal (10%, 1.00 g) and 5-(4-fluoro-phenyl)-4-methyl-pent-4-enoic acid ethyl ester (1.01 g) in ethanol (20 ml) was stirred for 2 h under an atmosphere of hydrogen. The reaction mixture was filtered (dicalite), and the solvent was evaporated. Upon evaporation of the solvent, 5-(4-fluoro-phenyl)-4-methyl-pentanoic acid ethyl ester was obtained; the compound was used in the next step without further purification. MS: m/e=239.3 [M+H+].

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