Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl iodoacetate → [2-(3-Trifluoromethoxy-phenyl)-ethoxy]-acetic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl iodoacetate | HCID 12183 | — |
| 반응물 | 2,6-Di-tert-butylpyridine | HCID 68510 | — |
| 반응물 | 2-(3-(Trifluoromethoxy)phenyl)ethanol | HCID 10632075 | — |
| 촉매 | Silver(I) trifluoromethanesulfonate | HCID 76223 | — |
| 생성물 | [2-(3-Trifluoromethoxy-phenyl)-ethoxy]-acetic acid ethyl ester | HCID 68569118 | — |
반응 단계
In analogy to the procedure described in example 78.1, 2-(3-trifluoromethoxy-phenyl)-ethanol was reacted with ethyl iodoacetate in the presence of silver trifluoromethanesulfonate and 2,6-di-tert-butylpyridin to give [2-(3-trifluoromethoxy-phenyl)-ethoxy]-acetic acid ethyl ester as colorless oil. MS: m/e=293.1 [M+H+].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07572801B2 |
| 출처 데이터셋 | uspto-grants-2009_08 |
| ORD ID | ord-e2c22870fd22443a9dc1c4ba3e99ebe3 |
| 출처 메모 | uspto-grants-2009_08 |