2,6-Difluoropyridine-3-carboxylic acid → HCID 135899205, compound

HRID 2100507Notes

Reaction equation

HRID 2100507 reaction equation
F[C:2]1[C:7]([C:8]([OH:10])=O)=[CH:6][CH:5]=[C:4]([F:11])[N:3]=1.Cl.[F:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][CH2:22][CH2:23][C:24]([NH2:26])=[NH:25])=[CH:16][CH:15]=1>>[F:11][C:4]1[CH:5]=[CH:6][C:7]2[C:8](=[O:10])[NH:26][C:24]([CH2:23][CH2:22][CH2:21][CH2:20][C:17]3[CH:16]=[CH:15][C:14]([F:13])=[CH:19][CH:18]=3)=[N:25][C:2]=2[N:3]=1

Participants

3

Reactant 2

HCID 105830702,6-Difluoropyridine-3-carboxylic acidHCID 68570207HCID 68570207, compound

Product 1

HCID 135899205HCID 135899205, compound

Procedure

The title compound was prepared in analogy to example 85 from 2,6-difluoropyridine-3-carboxylic acid and 5-(4-fluoro-phenyl)-pentanamidine hydrochloride. White solid. MS: m/e=316.1 [M+H+].

Sources & evidence

ORD record
ord-bebc70603ac14fe29708dbc9c4f75043
Source dataset
uspto-grants-2009_08
Patent number
US07572801B2

Reaction notes

Loading…