2,6-Difluoropyridine-3-carboxylic acid → HCID 136368386, compound

HRID 2100527Notes

Reaction equation

HRID 2100527 reaction equation
F[C:2]1[C:7]([C:8]([OH:10])=O)=[CH:6][CH:5]=[C:4]([F:11])[N:3]=1.Cl.[Cl:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH2:20][CH2:21][O:22][CH2:23][C:24]([NH2:26])=[NH:25]>>[Cl:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH2:20][CH2:21][O:22][CH2:23][C:24]1[NH:26][C:8](=[O:10])[C:7]2[CH:6]=[CH:5][C:4]([F:11])=[N:3][C:2]=2[N:25]=1

Participants

3

Reactant 2

HCID 105830702,6-Difluoropyridine-3-carboxylic acidHCID 68568905HCID 68568905, compound

Product 1

HCID 136368386HCID 136368386, compound

Procedure

The title compound was prepared in analogy to example 85 from 2,6-difluoropyridine-3-carboxylic acid and 2-[2-(2-chloro-phenyl)-ethoxy]-acetamidine hydrochloride. Light brown solid. MS: m/e=334.2 [M+H+].

Sources & evidence

ORD record
ord-42e09d6216e54607bb8d13ce7e14afa0
Source dataset
uspto-grants-2009_08
Patent number
US07572801B2

Reaction notes

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