HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 140520063, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 2,5-Dichloropyridine-3-carboxylic acid | HCID 2736085 | — |
| Reactant | HCID 68568905 | HCID 68568905 | — |
| Product | HCID 140520063 | HCID 140520063 | — |
Reaction Steps
In analogy to the procedure described in example 78.3, 2,5-dichloronicotinic acid was reacted with 2-[2-(2-chloro-phenyl)-ethoxy]-acetamidine hydrochloride (example 105.2) in the presence of TBTU and DIPEA to give 2,5-dichloro-N-{2-[2-(2-chloro-phenyl)-ethoxy]-1-imino-ethyl}-nicotinamide as orange oil. MS: m/e=388.1 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572801B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-14bac117aee046099feceb37a9bbaa37 |
| Source note | uspto-grants-2009_08 |