HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Diethyl 4-bromo-2-chlorobenzamide → (3aR,9bS)-tert-Butyl 6-chloro-4-methyl-5-oxo-8-propyl-3,3a,4,5-tetrahydro-1H-pyrrolo[3,4-c]isoquinoline-2(9bH)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Diethyl 4-bromo-2-chlorobenzamide | HCID 16115931 | — |
| Reactant | (3aR,9bS)-tert-butyl 6-chloro-5-oxo-8-propyl-3,3a,4,5-tetrahydro-1H-pyrrolo[3,4-c]isoquinoline-2(9bH)-carboxylate | HCID 69054699 | — |
| Product | (3aR,9bS)-tert-Butyl 6-chloro-4-methyl-5-oxo-8-propyl-3,3a,4,5-tetrahydro-1H-pyrrolo[3,4-c]isoquinoline-2(9bH)-carboxylate | HCID 69057014 | — |
Reaction Steps
Following the procedure described in Example 15, Part A, (3aR,9bS)-tert-butyl 6-chloro-5-oxo-8-propyl-3,3a,4,5-tetrahydro-1H-pyrrolo[3,4-c]isoquinoline-2(9bH)-carboxylate, the first eluting compound from Example 23, Part J, was converted into the title compound. LRMS (ESI): 379.17/381.15 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572805B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-55adb6805237496c86957255c7aa434b |
| Source note | uspto-grants-2009_08 |