4-Toluenesulfonyl chloride → HCID 57799482, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of NaOH (0.55 g, 13.64 mmol) in H2O (10 ml) was added 5,6-Bis-(2-methoxy-ethoxy)-indan-1,2-dione 2-oxime (1.11 g, 3.59 mmol), and the mixture was heated to 50° C. Then p-Toluenesulfonyl chloride (0.89 g, 4.66 mmol) was added in portions to the mixture, and then the mixture was heated at 80° C. for 15 min. After cooling careful to room temperature, the precipitate (a little) was filtered off, the filtrate was acidified by concentrated HCl to PH=3-4. The precipitate was collected and dried to give product (0.777 mg, yield 70%). LC-MS: m/e 208 (M−1).

Provenance & Evidence