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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2100765Generated: October 31, 2026

P-Cresol → (5-methyl-1H-pyrazol-3-yl)-(1-p-tolyloxy-isoquinolin-3-yl)-amine

https://huagongshe.com/reaction/2100765

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-CresolHCID 2879—
Reactant(1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799635—
Product(5-methyl-1H-pyrazol-3-yl)-(1-p-tolyloxy-isoquinolin-3-yl)-amineHCID 57799653—

Reaction Steps

Similar procedure as described in example 10 was used, starting from 4-methyl-phenol and (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (5-methyl-1H-pyrazol-3-yl)-(1-p-tolyloxy-isoquinolin-3-yl)-amine. LC-MS m/e 331 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-76f4270c9e4541f2863d1bee0da870e6
Source noteuspto-grants-2009_08