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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2100777Generated: October 26, 2026

Diethylene Glycol Monoethyl Ether → {-[2-(2-ethoxy-ethoxy)-ethoxy]-isoquinolin-3-yl}-(5-methyl-1H-pyrazol-3-yl)-amine

https://huagongshe.com/reaction/2100777

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylene Glycol Monoethyl EtherHCID 8146—
Reactant(1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799635—
Product{-[2-(2-ethoxy-ethoxy)-ethoxy]-isoquinolin-3-yl}-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799867—

Reaction Steps

Similar procedure as described in example 10 was used, starting from 2-(2-ethoxy-ethoxy)-ethanol and (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give {-[2-(2-ethoxy-ethoxy)-ethoxy]-isoquinolin-3-yl}-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 357(MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-f17f87d163374cf0ac10164c52095b9c
Source noteuspto-grants-2009_08