HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Piperidinoethanol → (5-methyl-1H-pyrazol-3-yl)-[1-(2-piperidin-1-yl-ethoxy)-isoquinolin-3-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Piperidinoethanol | HCID 18232 | — |
| Reactant | (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine | HCID 57799635 | — |
| Product | (5-methyl-1H-pyrazol-3-yl)-[1-(2-piperidin-1-yl-ethoxy)-isoquinolin-3-yl]-amine | HCID 57799562 | — |
Reaction Steps
Similar procedure as described in example 10 was used, starting from 2-piperidin-1-yl-ethanol and (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (5-methyl-1H-pyrazol-3-yl)-[1-(2-piperidin-1-yl-ethoxy)-isoquinolin-3-yl]-amine. LC-MS m/e 352(MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572809B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-eac7baf5aefb4da5b55f63281f856e05 |
| Source note | uspto-grants-2009_08 |