Diethylene Glycol Monoethyl Ether → HCID 57799529, compound

HRID 2100800Notes

Reaction equation

HRID 2100800 reaction equation
[CH2:1]([O:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][OH:9])[CH3:2].Cl[C:11]1[C:20]2[C:15](=[CH:16][C:17]([O:21][CH3:22])=[CH:18][CH:19]=2)[CH:14]=[C:13]([NH:23][C:24]2[CH:28]=[C:27]([CH3:29])[NH:26][N:25]=2)[N:12]=1>>[CH2:1]([O:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][O:9][C:11]1[C:20]2[C:15](=[CH:16][C:17]([O:21][CH3:22])=[CH:18][CH:19]=2)[CH:14]=[C:13]([NH:23][C:24]2[CH:28]=[C:27]([CH3:29])[NH:26][N:25]=2)[N:12]=1)[CH3:2]

Participants

3

Reactant 2

HCID 8146Diethylene Glycol Monoethyl EtherHCID 57799674(1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine

Product 1

HCID 57799529HCID 57799529, compound

Procedure

Similar procedure as described in example 10 was used, starting from 2-(2-ethoxy-ethoxy)-ethanol and (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give {1-[2-(2-ethoxy-ethoxy)-ethoxy]-6-methoxy-isoquinolin-3-yl}-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 387(MH+).

Sources & evidence

ORD record
ord-50f18c39b12a4b5ca0e9327a1c48ee2d
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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