4-Methoxyphenol → HCID 178492511, compound

HRID 2100801Notes

Reaction equation

HRID 2100801 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.Cl[C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[C:13]([NH:21][C:22]2[CH:26]=[CH:25][NH:24][N:23]=2)[N:12]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][C:11]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[CH:14]=[C:13]([NH:21][C:22]3[CH:26]=[CH:25][NH:24][N:23]=3)[N:12]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 90154-MethoxyphenolHCID 178478391HCID 178478391, compound

Product 1

HCID 178492511HCID 178492511, compound

Procedure

Similar procedure as described in example 10 was used, starting from 4-methoxy-phenol and (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine to give [1-(4-methoxy-phenoxy)-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine. LC-MS m/e 333(MH+).

Sources & evidence

ORD record
ord-823c36ce7aea4809b26fb3eedc55dab1
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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