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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2100806Generated: October 26, 2026

Cyclohexanol → (1-cyclohexyloxy-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine

https://huagongshe.com/reaction/2100806

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanolHCID 7966—
Reactant(1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799674—
Product(1-cyclohexyloxy-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amineHCID 57799486—

Reaction Steps

Similar procedure as described in example 10 was used, starting from cyclohexanol and (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (1-cyclohexyloxy-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 353(MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07572809B2
Source datasetuspto-grants-2009_08
ORD IDord-121ef99d49bc4d16b44484c1ab02c09d
Source noteuspto-grants-2009_08