Methanol → HCID 57799530, compound

HRID 2100820Notes

Reaction equation

HRID 2100820 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[C:18]([CH3:20])[NH:17][N:16]=2)[N:3]=1.[CH3:21][OH:22]>>[CH3:21][O:22][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[C:18]([CH3:20])[NH:17][N:16]=2)[N:3]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 57799818HCID 57799818, compound

Product 1

HCID 57799530HCID 57799530, compound

Procedure

Similar procedure as described in example 10 was used, starting from Methanol, (1-chloro-7-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (1-Methoxy-7-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 285(MH+).

Sources & evidence

ORD record
ord-cc98e28675964ca2a3aa32a500c61381
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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