Phenol → HCID 57799849, compound

HRID 2100829Notes

Reaction equation

HRID 2100829 reaction equation
[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl[C:9]1[C:18]2[C:13](=[C:14]([CH3:19])[CH:15]=[CH:16][CH:17]=2)[CH:12]=[C:11]([NH:20][C:21]2[CH:25]=[C:24]([CH3:26])[NH:23][N:22]=2)[N:10]=1>>[CH3:19][C:14]1[CH:15]=[CH:16][CH:17]=[C:18]2[C:13]=1[CH:12]=[C:11]([NH:20][C:21]1[CH:25]=[C:24]([CH3:26])[NH:23][N:22]=1)[N:10]=[C:9]2[O:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 996PhenolHCID 57799612HCID 57799612, compound

Product 1

HCID 57799849HCID 57799849, compound

Procedure

Similar procedure as described in example 10 was used, starting from phenol and (1-chloro-5-methyl-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine to give (5-methyl-1-phenoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 321(MH+).

Sources & evidence

ORD record
ord-1b8fb130fe2d4a66b1d68cbdec8a44c7
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

Loading…