M-Cresol → HCID 178425698, compound

HRID 2100848Notes

Reaction equation

HRID 2100848 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1.[CH3:18][C:19]1[CH:20]=[C:21]([OH:25])[CH:22]=[CH:23][CH:24]=1>>[NH:15]1[CH:16]=[CH:17][C:13]([NH:12][C:4]2[N:3]=[C:2]([O:25][C:21]3[CH:20]=[C:19]([CH3:18])[CH:24]=[CH:23][CH:22]=3)[C:11]3[C:6]([CH:5]=2)=[CH:7][CH:8]=[CH:9][CH:10]=3)=[N:14]1

Participants

3

Reactant 2

HCID 342M-CresolHCID 178478391HCID 178478391, compound

Product 1

HCID 178425698HCID 178425698, compound

Procedure

Similar procedure as described in example 10 was used, starting from (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and 3-methyl-phenol to give (1H-pyrazol-3-yl)-(1-m-tolyloxy-isoquinolin-3-yl)-amine. LC-MS m/e 317(MH+).

Sources & evidence

ORD record
ord-21d8b3f4978c4dd588e5fcdfe9c6617e
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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