Benzyl Alcohol → HCID 178487673, compound

HRID 2100867Notes

Reaction equation

HRID 2100867 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[CH:18][NH:17][N:16]=2)[N:3]=1.[C:20]1([CH2:26][OH:27])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:26]([O:27][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[CH:18][NH:17][N:16]=2)[N:3]=1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 178487533HCID 178487533, compound

Product 1

HCID 178487673HCID 178487673, compound

Procedure

Similar procedure as described in example 10 was used, starting from (1-chloro-6-methoxy-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and phenyl-methanol to give (1-benzyloxy-6-methoxy-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine. LC-MS m/e 347(MH+).

Sources & evidence

ORD record
ord-2d22acb307b04ee6ae58798519b2081e
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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