HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenylboronic acid → HCID 23633500, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine | HCID 57799635 | — |
| Product | HCID 23633500 | HCID 23633500 | — |
Reaction Steps
Similar procedure as described in example 131 was used, starting from (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and 4-fluoro-phenylboronic acid to give [1-(4-fluoro-phenyl)-isoquinolin-3-yl]-(5-methyl-1H-pyrazol-3-yl)-amine. LC-MS m/e 319(MH+). 1H NMR(CDCl3): δ 2.26(s, 3H), δ 5.89(s, 1H), δ 7.25(m, 3H), δ 7.32(br, 1H), δ 7.55(m, 1H), δ 7.65(s,1H), δ 7.70(m, 4H), δ 7.87(d,1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572809B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-cb281430d6514ffe88006c0912de55cd |
| Source note | uspto-grants-2009_08 |