1-Methyl-1H-pyrazole-4-boronic acid → (5-methyl-1H-pyrazol-3-yl)-[1-(1H-pyrazol-4-yl)-isoquinolin-3-yl]-amine

Participants

Role	Name	HCID	Charge
Reactant	1-Methyl-1H-pyrazole-4-boronic acid	HCID 11263501	—
Reactant	(1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine	HCID 57799635	—
Product	(5-methyl-1H-pyrazol-3-yl)-[1-(1H-pyrazol-4-yl)-isoquinolin-3-yl]-amine	HCID 57799752	—

Reaction Steps

Similar procedure as described in example 131 was used, starting from (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and N-methyl-pyrazole-4-boronic acid to give (5-methyl-1H-pyrazol-3-yl)-[1-(1H-pyrazol-4-yl)-isoquinolin-3-yl]-amine. LC-MS m/e 305(MH+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07572809B2
Source dataset	uspto-grants-2009_08
ORD ID	ord-48e778259b474b4a8c26dc5899c887ef
Source note	uspto-grants-2009_08