HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Pyridin-4-yl)boronic acid → (5-methyl-1H-pyrazol-3-yl)-(1-pyridin-4-yl-6-methoxy-isoquinolin-3-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Pyridin-4-yl)boronic acid | HCID 2734379 | — |
| Reactant | (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine | HCID 57799674 | — |
| Product | (5-methyl-1H-pyrazol-3-yl)-(1-pyridin-4-yl-6-methoxy-isoquinolin-3-yl)-amine | HCID 57799720 | — |
Reaction Steps
Similar procedure as described in example 131 was used, starting from (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and 4-pyridine-boronic acid to give (5-methyl-1H-pyrazol-3-yl)-(1-pyridin-4-yl-6-methoxy-isoquinolin-3-yl)-amine. LC-MS m/e 332(MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07572809B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-db2ae5ecb5b94cf1a9395f14173d06ce |
| Source note | uspto-grants-2009_08 |