4-Ethoxyphenylboronic acid → HCID 178466133, compound

HRID 2100988Notes

Reaction equation

HRID 2100988 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1.[CH2:18]([O:20][C:21]1[CH:26]=[CH:25][C:24](B(O)O)=[CH:23][CH:22]=1)[CH3:19]>>[CH2:18]([O:20][C:21]1[CH:26]=[CH:25][C:24]([C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH:5]=[C:4]([NH:12][C:13]3[CH:17]=[CH:16][NH:15][N:14]=3)[N:3]=2)=[CH:23][CH:22]=1)[CH3:19]

Participants

3

Reactant 2

HCID 27343514-Ethoxyphenylboronic acidHCID 178478391HCID 178478391, compound

Product 1

HCID 178466133HCID 178466133, compound

Procedure

Similar procedure as described in example 131 was used, starting from (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and 4-ethoxy-phenylboronic acid to give [1-(4-ethoxy-phenyl)-isoquinolin-3-yl]-(1H-pyrazol-3-yl)-amine. LC-MS m/e 331(MH+).

Sources & evidence

ORD record
ord-78d43d47a7e54c72b2d5e3f74530e687
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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