(Pyridin-4-yl)boronic acid → HCID 178419919, compound

HRID 2100993Notes

Reaction equation

HRID 2100993 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[CH:16][NH:15][N:14]=2)[N:3]=1.[N:18]1[CH:23]=[CH:22][C:21](B(O)O)=[CH:20][CH:19]=1>>[NH:15]1[CH:16]=[CH:17][C:13]([NH:12][C:4]2[N:3]=[C:2]([C:21]3[CH:22]=[CH:23][N:18]=[CH:19][CH:20]=3)[C:11]3[C:6]([CH:5]=2)=[CH:7][CH:8]=[CH:9][CH:10]=3)=[N:14]1

Participants

3

Reactant 2

HCID 2734379(Pyridin-4-yl)boronic acidHCID 178478391HCID 178478391, compound

Product 1

HCID 178419919HCID 178419919, compound

Procedure

Similar procedure as described in example 131 was used, starting from (1-chloro-isoquinolin-3-yl)-(1H-pyrazol-3-yl)-amine and 4-pyridinylboronic acid to give ((1H-pyrazol-3-yl)-(1-pyridin-4-yl-isoquinolin-3-yl)-amine. LC-MS m/e 288(MH+).

Sources & evidence

ORD record
ord-e679fd821c3f4e9d9517bb8f13063120
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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