4-Butyloxyaniline → HCID 57799891, compound

HRID 2101024Notes

Reaction equation

HRID 2101024 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:12][C:13]2[CH:17]=[C:16]([CH3:18])[NH:15][N:14]=2)[N:3]=1.[CH2:19]([O:23][C:24]1[CH:29]=[CH:28][C:27]([NH2:30])=[CH:26][CH:25]=1)[CH2:20][CH2:21][CH3:22]>>[CH2:19]([O:23][C:24]1[CH:25]=[CH:26][C:27]([NH:30][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[CH:5]=[C:4]([NH:12][C:13]3[CH:17]=[C:16]([CH3:18])[NH:15][N:14]=3)[N:3]=2)=[CH:28][CH:29]=1)[CH2:20][CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 203524-ButyloxyanilineHCID 57799635(1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine

Product 1

HCID 57799891HCID 57799891, compound

Procedure

Similar procedure as described in example 273 was used, starting from (1-chloro-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and 4-butoxy-phenylamine to give N1-(4-butoxy-phenyl)-N3-(5-methyl-1H-pyrazol-3-yl)-isoquinoline-1,3-diamine. LC-MS m/e 388(MH+).

Sources & evidence

ORD record
ord-a6ccdd192b994d5c88bd01c6e72de993
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

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