3-Ethylaniline → HCID 57799533, compound

HRID 2101030Notes

Reaction equation

HRID 2101030 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[CH:5]=[C:4]([NH:14][C:15]2[CH:19]=[C:18]([CH3:20])[NH:17][N:16]=2)[N:3]=1.[CH2:21]([C:23]1[CH:24]=[C:25]([NH2:29])[CH:26]=[CH:27][CH:28]=1)[CH3:22]>>[CH2:21]([C:23]1[CH:24]=[C:25]([NH:29][C:2]2[C:11]3[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=3)[CH:5]=[C:4]([NH:14][C:15]3[CH:19]=[C:18]([CH3:20])[NH:17][N:16]=3)[N:3]=2)[CH:26]=[CH:27][CH:28]=1)[CH3:22]

Participants

3

Reactant 2

HCID 114753-EthylanilineHCID 57799674(1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine

Product 1

HCID 57799533HCID 57799533, compound

Procedure

Similar procedure as described in example 273 was used, starting from (1-chloro-6-methoxy-isoquinolin-3-yl)-(5-methyl-1H-pyrazol-3-yl)-amine and 3-ethyl-phenylamine give N1-(3-ethyl-phenyl)-6-methoxy-N3-(5-methyl-1H-pyrazol-3-yl)-isoquinoline-1,3-diamine. LC-MS m/e 374(MH+).

Sources & evidence

ORD record
ord-bb3cc390f26a464e9db79393274fed55
Source dataset
uspto-grants-2009_08
Patent number
US07572809B2

Reaction notes

Loading…